Cervical lymph nodes are lymph nodes found in the neck
Example: Further analysis revealed significantly increased frequencies and numbers of Tfh cells, Tfr cells, and GC B cells in the cervical lymph nodes (CLNs) compared with control mice immunized with adjuvant[2].
ru: Шейные лимфатические узлы
ELISA
Enzyme-linked immunosorbent assay. Commonly used analytical biochemistry assay
Example: Sera were collected from virus-infected mice on day 9 after infection. Virus-specific antibodies were measured with ELISA as previously described[2].
ru: Иммуноферментный анализ
IL-2
Interleukin, a type of cytokine signaling molecule in the immune system.
Example: CD25- Tfr cells, mostly localized in the GCs and acting as the primary suppressive cells in established GCs, could be inhibited by high levels of IL-2 during the immune response. CD25+ Tfr cells, a precursor population mostly localized in the T cell zone
Immunohistochemical analysis
Method of microscopic examination of tissues, providing the most specific detection of the desired substances in them
Example: Immunohistochemical analysis was performed as previously described[3].
ru: Иммуногистохими́ческое иссле́дование
Knockout mice
Genetically modified mouse (Mus musculus) in which researchers have inactivated, or "knocked out", an existing gene by replacing it or disrupting it with an artificial piece of DNA
Example: KO mice 6–8 wk old were healthy and fertile, with Tfh and GC B cell populations comparable to those of WT mice[2].