A glossary is created for English Course at Skoltech
antibody
noun
a blood protein produced in response to and counteracting a specific antigen. Antibodies combine chemically with substances which the body recognizes as alien, such as bacteria, viruses, and foreign substances in the blood
Example: Thereafter, the tissues were incubated with fluorescent secondary antibody Alexa Fluor 568 (1:400 dilution, Invitrogen) [2].
2. Al Khazal F, Kang S, Nelson Holte M, Choi DS, Singh R, Ortega-Sáenz P, López-Barneo J, Maher LJ 3rd. Unexpected obesity, rather than tumorigenesis, in a conditional mouse model of mitochondrial complex II deficiency. FASEB J. 2021 Feb;35(2):e21227. doi: 10.1096/fj.202002100R. Epub 2020 Nov 27. PMID: 33247500; PMCID: PMC7861419.
en: антитело
epigenetics
noun
Epigenetics is the study of how your behaviors and environment can cause changes that affect the way your genes work.
Example: The resulting dysregulation of metabolism and epigenetics is tumorigenic in certain tissues [1].
1. Millán-Uclés Á, Díaz-Castro B, García-Flores P, et al. A condi- tional mouse mutant in the tumor suppressor SdhD gene unveils a link between p21WAF1/Cip1 induction and mitochondrial dys- function. PLoS One. 2014;9:e85528.
en: Эпигенетика
lethal
adjective
sufficient to cause death
Example: Brain tissues were isolated from male mice at 27 weeks of age following lethal exposure to carbon dioxide and perfu- sion with saline and 4% paraformaldehyde (PFA) in PBS solution [2].
2. Al Khazal F, Kang S, Nelson Holte M, Choi DS, Singh R, Ortega-Sáenz P, López-Barneo J, Maher LJ 3rd. Unexpected obesity, rather than tumorigenesis, in a conditional mouse model of mitochondrial complex II deficiency. FASEB J. 2021 Feb;35(2):e21227. doi: 10.1096/fj.202002100R. Epub 2020 Nov 27. PMID: 33247500; PMCID: PMC7861419.
en: Летальный, смертельный
receptor
noun
an organ or cell able to respond to light, heat, or other external stimulus and transmit a signal to a sensory nerve
Example: The fact that PPGL patients with catecholamine elevation do not generally demonstrate a corresponding increased metabolism with weight loss may also reflect receptor downregulation [2].
2. Al Khazal F, Kang S, Nelson Holte M, Choi DS, Singh R, Ortega-Sáenz P, López-Barneo J, Maher LJ 3rd. Unexpected obesity, rather than tumorigenesis, in a conditional mouse model of mitochondrial complex II deficiency. FASEB J. 2021 Feb;35(2):e21227. doi: 10.1096/fj.202002100R. Epub 2020 Nov 27. PMID: 33247500; PMCID: PMC7861419.
en: рецептор
serum
noun
an amber-coloured, protein-rich liquid which separates out when blood coagulates
Example: Fasting blood serum from seven experimental male mice and a matching number of controls (age 27 weeks) was an- alyzed to determine fasting insulin levels using a commer- cial ELIZA kit (Novus biological #NBP2-62853) [2].
2. Al Khazal F, Kang S, Nelson Holte M, Choi DS, Singh R, Ortega-Sáenz P, López-Barneo J, Maher LJ 3rd. Unexpected obesity, rather than tumorigenesis, in a conditional mouse model of mitochondrial complex II deficiency. FASEB J. 2021 Feb;35(2):e21227. doi: 10.1096/fj.202002100R. Epub 2020 Nov 27. PMID: 33247500; PMCID: PMC7861419.