Example: n this regard, it is crucial that NPs are bestowed with a sturdy biomimicry demeanour along with the attitude to pointedly target the diseased tissues.
en: даровать
considerable
adjective
notably large in size, amount, or extent
Example: Lately, a considerable research focus has been devoted by the scientific community toward the engineering of the surface properties of polymeric nanoparticles (NPs) intended for cancer therapy.
en: значительный
here we aimed to correlate
phrase
Example: Thus, here we aimed to correlate the MW of HA externally exposed and physically linked to poly(lactic-co-glycolic acid) (PLGA)-based NPs to their internalization kinetics in CD44 overexpressing cells.
en: здесь мы стремились коррелировать
In addition, the well-known biocompatibility, biodegradability and non-immunogenicity of ... makes it an extremely attractive material for ...
phrase
Example: In addition, the well-known biocompatibility, biodegradability and non-immunogenicity of HA makes it an extremely attractive material for the surface decoration of nanoplatforms designed to be equipped with active tumour targeting properties.
en: Кроме того, известная биосовместимость, биоразлагаемость и неиммуногенность ... делает его чрезвычайно привлекательным материалом для ...
In this scenario
phrase
Example: In this scenario, the molecular weight of HA can be envisaged as a paramount design parameter in the engineering of nanoplatforms intended for active tumour targeting.
en: В этом сценарии
lesion
noun
a region in an organ or tissue which has suffered damage through injury or disease, such as a wound, ulcer, abscess, or tumour
Example: For example, less than 0.01% of non-targeted drugs do actually reach cancerous lesions after systemic intravenous administration.
en: поражение
More in detail, ... possesses a strong tropism toward ...
phrase
Example: More in detail, HA possesses a strong tropism toward solid tumors due to its aptitude for a specialized interplay with CD44 receptors, which are overexpressed on the cytoplasmatic membrane of a wide array of tumour cell populations.
en: Подробнее, ... обладает сильным тропизмом в направлении ...
quantify
verb
express or measure the quantity of
Example: NP internalization kinetics in CD44-overexpressing breast carcinoma cells were quantified, using healthy fibroblast cells as reference.
en: определять количество
This result points at a preferential interaction between
phrase
en: Этот результат указывает на предпочтительное взаимодействие между
uptake
noun
the taking in or absorption of a substance by a living organism or bodily organ
Example: Here we aimed to correlate different molecular weights of hyaluronic acid (HA), 200, 800 and 1437 kDa, used to decorate poly(lactic-co-glycolic acid) (PLGA)-based nanoparticles (NPs), to their cell uptakes.
